AuthorWrite something about yourself. No need to be fancy, just an overview. ArchivesCategories |
Back to Blog
Flowjo 10 mfi2/14/2023 coli in term neonates (> 37 week n = 13). ROS production was induced by fMLP, PMA and E. Percentage (%) of cells expressing surface marker (HLA-DR, CD11b, CD62L, CD32, Toll-Like-Receptor-2) and expression per cell, determined by mean fluorescence intensity (MFI), were measured by flow cytometry. In a prospective, longitudinal study granulocyte and monocyte subpopulations were analysed in healthy term infants (> 37 week n = 13) in comparison with healthy young adults ( n = 11). Therefore, reactive oxygen species (ROS) and surface activation markers were quantified in subpopulations. We here analysed the function of classical, pro- and anti-inflammatory monocytes and granulocytes from neonates in comparison with adults to investigate if suppressed functions of subpopulations are causative for the unique neonatal immune status. This could be either defect or protective mechanism against overshooting proinflammatory immune responses. Neonate immune cell functions lack full protection against pathogens.
0 Comments
Read More
Leave a Reply. |